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De novo genes in the human genome: Origin, roles, and evolution a CNS perspective

1.0. Introduction: There are numerous striking instances of functional novelty linked to phenotypes that have changed from their ancestral states, making it difficult to determine the evolutionary origins of the derived features. The development of wing patterns in Drosophila, the formation of feathers in birds, and the origin of the vertebrate inner ear, which was …

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Development of Polypropylene Plastic Wastes into Emulsion Paint Binder for Water-Resistant Emulsion Paint Formulation

1. INTRODUCTION Plastics have become indispensable in modern society, serving a multitude of purposes from agriculture to packaging [1]. However, the rampant accumulation of plastic waste globally has triggered significant environmental concerns [2]. Plastic waste not only blights landscapes but also infiltrates water bodies and oceans, with an estimated 1.1 to 8.8 million tonnes entering …

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The Impact of Exercise on Cognitive Function: A Comprehensive Review

Introduction Cognitive health has become an increasingly relevant concern as societies face escalating academic, occupational, and aging-related demands on mental function.  Research continuously reveals that cognitive skills such as attention, memory, and executive control are crucial for learning, decision-making, and general quality of life [1, 2].  At the same time, worldwide trends reveal a growing …

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The Influence of School and Social Factors and Social Media Use on Mental Health Literacy and Help-Seeking Behaviors among Thai Adolescents

1. Introduction Adolescence represents a formative developmental stage marked by profound emotional, psychological, and social transitions. During this period, individuals undergo rapid changes in self-concept, peer relationships, and academic demands, which may heighten susceptibility to psychological stress and mental health difficulties [3]. At a global level, common mental health conditions such as anxiety and depressive …

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Human Exposure to Endocrine-Disrupting Chemicals: A Review of Sources, Health Effects, and Biomonitoring Strategies

1. Introduction Endocrine-disrupting chemicals (EDCs) are exogenous agents that interfere with the normal function of the endocrine system by altering hormone synthesis, secretion, transport, metabolism, receptor binding, or signal transduction. These compounds include a broad range of synthetic and naturally occurring chemicals that humans encounter in everyday life. Growing evidence that EDCs can have biological …

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Immunosuppressive Potential of Co-Administration of Azathioprine and brown Seaweed Extracts on Inflammatory Biomarkers in Rheumatoid Arthritis; A Systematic Review

1.     Introduction 18 million people around the globe suffered from rheumatoid arthritis in 2019. Rheumatoid arthritis affects about 70% of women, and 55% of those affected are over 55. Rheumatoid arthritis affects 13 million people, with moderate to severe symptoms that may benefit from rehabilitation [2023]. Based on self-reported data from the National Health Survey …

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Developmental Implications of USAID Funding Suspension in Northeastern and North Central Nigeria: An Analysis of Conflict-Related Deaths (2021–2025)

Introduction Global security challenges are evolving in scope, complexity, and consequences, thus creating humanitarian crises that transcend borders and affect vulnerable populations across Continents, Regional, Sub-Regional and National lines. Its outcome overtly and covertly undermines peace, stability, and development while exacerbating human suffering in conflict-affected regions like Northeast and North Central Nigeria17. The prevalence of …

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Differential Effect of Fresh and Dried Jatropha tanjorensis Leaves on Dichlorvos- Induced Renal Injury

1. Introduction The increasing use of synthetic pesticides in agriculture and domestic pest control has raised serious public health and environmental concerns. Among these chemicals, dichlorvos (2,2- dichlorovinyl dimethyl phosphate; DDVP) is a widely used organophosphate insecticide due to its rapid insecticidal action and broad-spectrum efficacy. However, extensive evidence indicates that DDVP exposure poses significant …

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Extraction and Utilization of Colorants From Tea Leaf Fibre in The Formulation of Shelf-Stable Local Beverages

Tea (Camellia sinensis) leaves yield extracts rich in polyphenols (10-13%) and caffeine (2-4%) [9; 34], known for strong antioxidant properties and diverse human health benefits [13]. The specific chemical profile varies with cultivar and processing [34; 27]. The global scale of tea production results in massive quantities of spent tea leaf (STL) or spent tea …

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Stress and Breastfeeding: Implication for Maternal and Infant Health

Introduction Breastfeeding is a critical phase for both the mother and infant. This period often presents numerous physiological and psychological challenges that are predominantly stress related. Postpartum stress and anxiety can stem from various factors, including hormonal changes, the demands of caring for a newborn, and adjustments to new family dynamics7. These psychological conditions not …

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