Impact of the DNA Fragmentation Index on some Characteristic Parameters of Sperm Quality
Modou Mamoune Mbaye* , Ben Salah Kamal , Achraf Zakaria , Mustafa Zakaria , Bouchra ElKhalfi , Mohammed Zarqoui , Abdelaziz Soukri , Noureddine Louanjli
Abstract
The DNA fragmentation index (DFI) is an essential factor in assessing the quality of the genetic material of human sperm. Its influence on the characteristic parameters of sperm quality remains a matter of debate. Ours work aim to find a correlation between the DNA fragmentation index and the characteristic parameters of sperm quality, namely: sperm count, motility, vitality, and morphology. The results showed a coefficient of determination between 0.11 and 0.17 suggesting a weakly negative correlation between DFI and motility, vitality, and even count. The correlation found between the sperm DNA fragmentation index and the rate of morphologically abnormal spermatozoa was much weaker, suggesting an absence of correlation.
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The DNA fragmentation index (DFI) is an essential factor in assessing the quality of the genetic material of human sperm. Its influence on the characteristic parameters of sperm quality remains a matter of debate. Ours work aim to find a correlation between the DNA fragmentation index and the characteristic parameters of sperm quality, namely: sperm count, motility, vitality, and morphology. The results showed a coefficient of determination between 0.11 and 0.17 suggesting a weakly negative correlation between DFI and motility, vitality, and even count. The correlation found between the sperm DNA fragmentation index and the rate of morphologically abnormal spermatozoa was much weaker, suggesting an absence of correlation.