Efficacy of Polyherbal Unani Formulation in ehtebas-e-haiz [amenorrhoea]-a Randomised Single Blind Study

Shaik Akeefa Nousheen*

DOI : 10.46890/SL.2020.v01i04.005

Abstract

Introduction: Amenorrhoea denotes absence of menstruation. Primary amenorrhoea refers to failure of onset of menstruation beyond the age of 16 years regardless development of secondary sexual characters. Secondary amenorrhoea refers to failure to occurrence of menstruation for 6 months or longer in women who have previously menstruated Primary amenorrhoea is rare about 0.3%, whereas secondary amenorrhoea is about 30-40%.According to Shaik ur Rayees Bu Ali Sena in his book “Al Qanoon Fit Tibb” amenorrhoea is cessation of menstrual flow which may be due to uterine pathology or due to altered temperament of the body.Hk Ashrafuddin Ismail Jurjani in his book Zaqir-e-Qarzam Shahi stated that any imbalance in humours(khilt) will lead to change in temperament of body which causes amenorrhoea.He stated that the hot temperament leads to dryness and constriction of the blood vessels and cold temperament causes increase in the viscosity of the blood which leads to ehtebas e haiz. Objective: To see the efficacy of unani formulation in patients with ehtebas-e-haiz. Methodology: Study was conducted in Dept of Amraze Niswan at Govt Nizamia Tibbi College and hospital, Hyderabad. 100 patients of reproductive were selected. An inclusion criterion includes women of age group 11-40 years with delayed peiods for 2-6 months. Exclusion criteria were pregnant women, menopause, and women with congenital anomalies, systemic disease and genetic disorders. A polyherbal unani formulation was made which consist of single drugs in the form of joshanda(tukhme karafs, aneesun, badiyan, pudina khushk, mishktaramsheey, abhal, parsiaoshaan),Qurs (Murmaki, pudina khushk, barge sadab, mishktaramsheey, majeeth, heeng, jaosheer, sakbeenj, each 3 gms) and humool (Zafraan,Ood-e-shireen, Nagarmotha) was given for 10 days for three consecutive cycles. Results: Primary outcome was withdrawal bleeding which was seen in 63 patients out of 100 patients and secondary outcome was regularisation of cycle which was seen in 37 patients in first cycle. Conclusion: The study proved efficacy of unani formulation with good results without any side effects. The formulation can also be used as an alternate to the OCP which are used for withdrawal in conventional medicine.

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Introduction: Amenorrhoea denotes absence of menstruation. Primary amenorrhoea refers to failure of onset of menstruation beyond the age of 16 years regardless development of secondary sexual characters. Secondary amenorrhoea refers to failure to occurrence of menstruation for 6 months or longer in women who have previously menstruated Primary amenorrhoea is rare about 0.3%, whereas secondary amenorrhoea is about 30-40%.According to Shaik ur Rayees Bu Ali Sena in his book “Al Qanoon Fit Tibb” amenorrhoea is cessation of menstrual flow which may be due to uterine pathology or due to altered temperament of the body.Hk Ashrafuddin Ismail Jurjani in his book Zaqir-e-Qarzam Shahi stated that any imbalance in humours(khilt) will lead to change in temperament of body which causes amenorrhoea.He stated that the hot temperament leads to dryness and constriction of the blood vessels and cold temperament causes increase in the viscosity of the blood which leads to ehtebas e haiz. Objective: To see the efficacy of unani formulation in patients with ehtebas-e-haiz. Methodology: Study was conducted in Dept of Amraze Niswan at Govt Nizamia Tibbi College and hospital, Hyderabad. 100 patients of reproductive were selected. An inclusion criterion includes women of age group 11-40 years with delayed peiods for 2-6 months. Exclusion criteria were pregnant women, menopause, and women with congenital anomalies, systemic disease and genetic disorders. A polyherbal unani formulation was made which consist of single drugs in the form of joshanda(tukhme karafs, aneesun, badiyan, pudina khushk, mishktaramsheey, abhal, parsiaoshaan),Qurs (Murmaki, pudina khushk, barge sadab, mishktaramsheey, majeeth, heeng, jaosheer, sakbeenj, each 3 gms) and humool (Zafraan,Ood-e-shireen, Nagarmotha) was given for 10 days for three consecutive cycles. Results: Primary outcome was withdrawal bleeding which was seen in 63 patients out of 100 patients and secondary outcome was regularisation of cycle which was seen in 37 patients in first cycle. Conclusion: The study proved efficacy of unani formulation with good results without any side effects. The formulation can also be used as an alternate to the OCP which are used for withdrawal in conventional medicine.