Three coronaviruses have caused catastrophic outbreaks of pneumonia in humans since early 21st century. The latest Covid-19 (Coronavirus disease 2019) is the third zoonotic origin coronavirus outbreak to occur in the current century that spread from one city in china to the whole world within 30 days. Corona virus is the re-emerging virus, which has spread in a very deadly way nowadays. It is now known that the SARS-CoV2 genome has a structural similarity of 96.2 per cent to a bat coronavirus (CoVRaTG13) and 79.5 per cent to SARS-CoV, respectively. Approximately 50-80 per cent of the virus transmission comes from asymptomatic carriers and speech droplets transmission is considered to be a major mode of disease transmission. Unani and Veterinary services should work together to exchange information and conduct a risk assessment using a One Health approach when a person who is infected with SARSCoV2 reports is in touch with their pets or animals. Before the era of chemical air purifiers, Unani physicians used medicinal herbs as decoction or distillate for spray or as fumigants to keep the air free from pollutants. Various unani herbs like vinegar and some aromatic drugs can kill infectious agents and should be used as fumigants during epidemics. Hand hygiene, food hygiene, avoid consumption of bushmeat are some veterinary’s preventive measures which help to control the infection during epidemic conditions.